84445-38-5

84445-38-5 structure

Name: 2',3'-dideoxyuridine-5'-triphosphate
Chemical Name: Deoxyuridine triphosphate
CAS Number: 84445-38-5
Molecular Formula: C₉H₁₅N₂O₁₃P₃
Molecular Weight: 452.14
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2016-03-15 08:30:50
Modify Date: 2024-04-03 17:40:13
ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) is a selective HIV and AMV reverse transcriptase inhibitor with Ki values of 0.05 µM and 1 µM, respectively. ddUTP is incorporated into the growing DNA strand primarily at dTTP sites and inhibits further elongation[1].

Name	Deoxyuridine triphosphate

Description	ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) is a selective HIV and AMV reverse transcriptase inhibitor with Ki values of 0.05 µM and 1 µM, respectively. ddUTP is incorporated into the growing DNA strand primarily at dTTP sites and inhibits further elongation[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> Reverse Transcriptase
References	[1]. Hao Z, Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate. Mol Pharmacol. 1990 Feb;37(2):157-63.