149234-05-9

149234-05-9 structure
149234-05-9 structure
  • Name: H-ILE-ARG-VAL-VAL-MET-OH
  • Chemical Name: h-ile-arg-val-val-met-oh
  • CAS Number: 149234-05-9
  • Molecular Formula: C27H52N8O6S
  • Molecular Weight: 616.81700
  • Catalog: Research Areas Cancer
  • Create Date: 2016-02-18 16:05:43
  • Modify Date: 2024-01-12 20:54:14
  • H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor[1][2].

Name h-ile-arg-val-val-met-oh
Synonyms ile-arg-val-val-met
Description H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor[1][2].
Related Catalog
Target

Thrombospondin-1 (TS1) receptor[2]

In Vitro H-ILE-ARG-VAL-VAL-MET-OH 支持 G361 黑色素瘤、K562 红白血病细胞、HT1080 纤维肉瘤、C32 无色素黑色素瘤和内皮细胞的附着。H-ILE-ARG-VAL-VAL-MET-OH 还抑制细胞与 TS1 的重组细胞结合域 (CBD) 的粘附[1]。
References

[1]. Kosfeld MD, et al. Identification of a new cell adhesion motif in two homologous peptides from the COOH-terminal cell binding domain of human thrombospondin. J Biol Chem. 1993 Apr 25;268(12):8808-14.  

[2]. Frazier, et al. Thrombospondin 1 subfragments that bind to thrombospondin 1 receptor and inhibit cell adhesion: United States, US5399667[P]. 1995-03-21.

Molecular Formula C27H52N8O6S
Molecular Weight 616.81700
Exact Mass 616.37300
PSA 266.92000
LogP 3.16680