- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: NH2-C4-NH-Boc
- Price: ￥558.0/5g ￥178.0/1g
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: tert-Butyl N-(4-aminobutyl)carbamate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
68076-36-8
68076-36-8 structure
- Name: NH2-C4-NH-Boc
- Chemical Name: tert-Butyl N-(4-aminobutyl)carbamate
- CAS Number: 68076-36-8
- Molecular Formula: C9H20N2O2
- Molecular Weight: 188.267
- Catalog: Organic raw materials Amino compound Acyclic monoamines, polyamines and their derivatives and salts
- Create Date: 2018-07-13 14:20:15
- Modify Date: 2024-01-02 20:41:10
-
NH2-C4-NH-Boc (compound 15) is a PROTAC linker, which refers to the Alkyl/ether composition. NH2-C4-NH-Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Name | tert-Butyl N-(4-aminobutyl)carbamate |
|---|---|
| Synonyms |
2-Methyl-2-propanyl (4-aminobutyl)carbamate
BOC-NH(CH2)4NH2 HCL tert-butyl 4-aminobutylcarbamate Carbamic acid, N-(4-aminobutyl)-, 1,1-dimethylethyl ester (4-amino-butyl)-carbamic acid tert-butyl ester N-(1,1-dimethylethoxycarbonyl)-1,4-butanediamine BOC-DIAMINOBUTANE HCL N-Boc-1,4-butanediamine N-Boc-1,4-butandiamine N-T-BOC-BUTANDIAMINE HCL (4-aminobutyl)carbamic acid 1,1-dimethylethyl ester BUTTPARK 121 6-09 RARECHEM AR PA 0023 tert-ButylN-(4-aminobutyl)carbamate 4-(t-butoxycarbonylamino)butylamine N-BOC-1,4-DIAMINOBUTANE AURORA KA-4397 N-(tert-butoxycarbonyl)-1,4-diamino-butane BOC-DAB HCL N-tert-Butoxycarbonyl-1,4-butanediamine MFCD02090802 tert-butyl 4-amino butylcarbamate |
| Description | NH2-C4-NH-Boc (compound 15) is a PROTAC linker, which refers to the Alkyl/ether composition. NH2-C4-NH-Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 292.9±23.0 °C at 760 mmHg |
| Molecular Formula | C9H20N2O2 |
| Molecular Weight | 188.267 |
| Flash Point | 130.9±22.6 °C |
| Exact Mass | 188.152481 |
| PSA | 64.35000 |
| LogP | 1.06 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.457 |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 2735 8/PG 3 |
| WGK Germany | 3 |
| Hazard Class | 8.0 |
| HS Code | 2924199090 |
| Precursor 9 | |
|---|---|
| DownStream 9 | |
![2-[[(tert-butoxycarbonyl)oxy]imino]-2-phenylacetonitrile structure](https://www.chemsrc.com/caspic/059/73371-96-7.png)
![Carbamic acid, [4-(ethylamino)butyl]-, 1,1-dimethylethyl ester (9CI) structure](https://www.chemsrc.com/caspic/175/780802-42-8.png)
![tert-butyl N-[4-(2-cyanoethylamino)butyl]carbamate structure](https://www.chemsrc.com/caspic/163/68076-40-4.png)
![tert-butyl N-[4-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]butyl]carbamate structure](https://www.chemsrc.com/caspic/457/404004-37-1.png)
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |