Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Isoxicam
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Purity: 99.0%
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DC Chemicals Limited
China
Product Name: Isoxicam
Price: ￥500.0/100mg ￥750.0/250mg ￥1500.0/1g
Purity: 98.0%
Stocking Period: 1 Day
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: Isoxicam
Price: ￥Inquiry/1g
Purity: 98.9%
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Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: Isoxicam
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Purity: 97.0%
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Contact: Xiyao Wang
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34552-84-6

34552-84-6 structure

34552-84-6 structure

Name: Isoxicam
Chemical Name: isoxicam
CAS Number: 34552-84-6
Molecular Formula: C₁₄H₁₃N₃O₅S
Molecular Weight: 335.335
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2018-05-13 08:00:00
Modify Date: 2025-08-21 18:15:57
Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis[1]. Isoxicam is a nonselective inhibitor of COX-1 and COX-2[2].

Name	isoxicam
Synonyms	2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-, 1,1-dioxide Isoxicam Isoxicamo [INN-Spanish] 4-Hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide 4-hydroxy-2-methyl-N-(5-methylisoxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide Isoxicamo 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide N-(5-methyl-3-isoxazolyl)-4-hydroxy-2-methyl-2H-1,2-benzthiazine-3-carboxamide 1,1-dioxide EINECS 252-084-5 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-1λ<sup>6</sup>,2-benzothiazine-3-carboxamide Isoxicamum [INN-Latin] Maxicam UNII:8XU734C4NG Pacyl (antiinflammatory) Isoxicamum UNII-8XU734C4NG 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide

Description	Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis[1]. Isoxicam is a nonselective inhibitor of COX-1 and COX-2[2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-1 COX-2
References	[1]. DiPasquale G, et al. The antiinflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide). Agents Actions. 1975 Aug;5(3):256-63. [2]. Xu S, et al. Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. J Biol Chem. 2014 Mar 7;289(10):6799-808.

Density	1.6±0.1 g/cm3
Boiling Point	518.8ºC at 760mmHg
Melting Point	265-271℃
Molecular Formula	C₁₄H₁₃N₃O₅S
Molecular Weight	335.335
Flash Point	267.5ºC
Exact Mass	335.057587
PSA	121.12000
LogP	1.38
Index of Refraction	1.686

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL0703000

CHEMICAL NAME :: 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-, 1,1-dioxide

CAS REGISTRY NUMBER :: 34552-84-6

LAST UPDATED :: 199706

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H13-N3-O5-S

MOLECULAR WEIGHT :: 335.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70- Volume(issue)/page/year: 7,481,1977

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	DL0703000

Precursor 9
50617-24-8 1072-67-9 35511-15-0 6639-62-9
59826-53-8 59826-54-9 128-44-9 24683-21-4
24683-26-9
DownStream 0

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