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61278-30-6

61278-30-6 structure
61278-30-6 structure
  • Name: D-Saccharic acid 1,4-lactone hydrate
  • Chemical Name: (2S)-2-[(3R,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetic acid,hydrate
  • CAS Number: 61278-30-6
  • Molecular Formula: C6H10O8
  • Molecular Weight: 192.12400
  • Catalog: Biochemical Carbohydrate Monosaccharide
  • Create Date: 2018-04-20 08:00:00
  • Modify Date: 2024-01-09 11:33:40
  • D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard drug compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].

Name (2S)-2-[(3R,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetic acid,hydrate
Synonyms D-Saccharolactone
D-Saccharic acid 1,4-lactone monohydrate
D-Glucaro-1,4-lactone Monohydrate
1,4-Lactone-D-glucaric Acid Monohydrate
D-Glucaro-1,4-lacton
D-Glucaric acid-1,4-lactone
MFCD00149334
Description D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard drug compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].
Related Catalog
References

[1]. Taha M, et al. Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs. Bioorg Chem. 2016;68:56-63.

[2]. Bhattacharya S, et al. Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. J Biochem Mol Toxicol. 2011;25(6):341-354.

Melting Point 80-82ºC
Molecular Formula C6H10O8
Molecular Weight 192.12400
Exact Mass 192.02700
PSA 124.29000
Storage condition 2-8°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
HS Code 2932190090
HS Code 2932190090
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%