D-Saccharic acid 1,4-lactone hydrate

Modify Date: 2024-01-09 11:33:40

D-Saccharic acid 1,4-lactone hydrate structure	Common Name	D-Saccharic acid 1,4-lactone hydrate
	CAS Number	61278-30-6	Molecular Weight	192.12400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆H₁₀O₈	Melting Point	80-82ºC
	MSDS	Chinese USA	Flash Point	N/A

Use of D-Saccharic acid 1,4-lactone hydrate

D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard drug compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].

Name	(2S)-2-[(3R,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetic acid,hydrate
Synonym	More Synonyms

Description	D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard drug compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Taha M, et al. Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs. Bioorg Chem. 2016;68:56-63. [2]. Bhattacharya S, et al. Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. J Biochem Mol Toxicol. 2011;25(6):341-354.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Taha M, et al. Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs. Bioorg Chem. 2016;68:56-63.

[2]. Bhattacharya S, et al. Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. J Biochem Mol Toxicol. 2011;25(6):341-354.

Melting Point	80-82ºC
Molecular Formula	C₆H₁₀O₈
Molecular Weight	192.12400
Exact Mass	192.02700
PSA	124.29000
Storage condition	2-8°C

D-Saccharic acid 1,4-lactone hydrate MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
HS Code	2932190090

HS Code	2932190090
Summary	2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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D-Saccharolactone

D-Saccharic acid 1,4-lactone monohydrate

D-Glucaro-1,4-lactone Monohydrate

1,4-Lactone-D-glucaric Acid Monohydrate

D-Glucaro-1,4-lacton

D-Glucaric acid-1,4-lactone

MFCD00149334