80529-93-7

80529-93-7 structure

Name: GADOPENTETIC ACID
Chemical Name: gadopentetic acid
CAS Number: 80529-93-7
Molecular Formula: C₁₄H₂₀GdN₃O₁₀
Molecular Weight: 547.57300
Catalog: API Diagnostic medication Image inspection medication
Create Date: 2018-05-16 08:00:00
Modify Date: 2024-01-02 20:10:27
Gadopentetic acid (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies. The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI. [Gd-DTPA0] is related to the administered bolus dose and varies with subjects. A bolus of 0.025 mmol/kg Gd-DTPA offers shorter acquisition time and less exposure of subjects, with a half-life of 37.3 mins, a mean residence time of 53.8 mins, and an AUC of 3.37 ± 0.47 mmol/min/L[1].

Name	gadopentetic acid
Synonyms	gadolinium diethylenetriaminepentaacetic acid Acido gadopentetico GADOPENTETATE Gd acid spray Acide gadopentetique Acidum gadopenteticum Gd(diethylenetriaminepentaacetic acid(-3H)) gadolinium 1,1,4,7,7-diethylenetriaminepentaacetate gadoliniumdtpa Gd-DTPA Gadopentetic

Description	Gadopentetic acid (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies. The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI. [Gd-DTPA0] is related to the administered bolus dose and varies with subjects. A bolus of 0.025 mmol/kg Gd-DTPA offers shorter acquisition time and less exposure of subjects, with a half-life of 37.3 mins, a mean residence time of 53.8 mins, and an AUC of 3.37 ± 0.47 mmol/min/L[1].
Related Catalog	Research Areas >> Others
References	[1]. Wan C, et al. Gd-DTPA-induced dynamic metabonomic changes in rat biofluids. Magn Reson Imaging. 2017 Dec;44:15-25. [2]. Taheri S, et al. Analysis of pharmacokinetics of Gd-DTPA for dynamic contrast-enhanced magnetic resonance imaging. Magn Reson Imaging. 2016 Sep;34(7):1034-40.