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18016-80-3

18016-80-3 structure
18016-80-3 structure
  • Name: S-(-)-LISURIDE
  • Chemical Name: lisuride
  • CAS Number: 18016-80-3
  • Molecular Formula: C24H32N4O5
  • Molecular Weight: 456.53500
  • Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
  • Create Date: 2018-08-03 11:16:19
  • Modify Date: 2024-01-08 11:39:50
  • Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels[1][2].

Name lisuride
Synonyms Lisurida
LISURIDE
3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea
Methylergol Carbamide
Lisuridum
Lysuride
Lysurid
Description Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels[1][2].
Related Catalog
Target

D2 Receptor

In Vivo lisuride (30~100 μg/kg) decreases the rate of dopa formation[2].
References

[1]. Rinne UK. Lisuride, a dopamine agonist in the treatment of early Parkinson's disease. Neurology. 1989;39(3):336-339.

[2]. Kehr W. Effect of lisuride and other ergot derivatives on monoaminergic mechanisms in rat brain. Eur J Pharmacol. 1977;41(3):261-273.

Density 1.23g/cm3
Boiling Point 603.4ºC at 760mmHg
Molecular Formula C24H32N4O5
Molecular Weight 456.53500
Flash Point 318.7ºC
Exact Mass 456.23700
PSA 125.97000
LogP 2.97230
Vapour Pressure 1.9E-15mmHg at 25°C
Index of Refraction 1.659