S-(-)-LISURIDE

Modify Date: 2024-01-08 11:39:50

S-(-)-LISURIDE Structure
S-(-)-LISURIDE structure
Common Name S-(-)-LISURIDE
CAS Number 18016-80-3 Molecular Weight 456.53500
Density 1.23g/cm3 Boiling Point 603.4ºC at 760mmHg
Molecular Formula C24H32N4O5 Melting Point N/A
MSDS N/A Flash Point 318.7ºC

 Use of S-(-)-LISURIDE


Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels[1][2].

 Names

Name lisuride
Synonym More Synonyms

 S-(-)-LISURIDE Biological Activity

Description Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels[1][2].
Related Catalog
Target

D2 Receptor

In Vivo lisuride (30~100 μg/kg) decreases the rate of dopa formation[2].
References

[1]. Rinne UK. Lisuride, a dopamine agonist in the treatment of early Parkinson's disease. Neurology. 1989;39(3):336-339.

[2]. Kehr W. Effect of lisuride and other ergot derivatives on monoaminergic mechanisms in rat brain. Eur J Pharmacol. 1977;41(3):261-273.

 Chemical & Physical Properties

Density 1.23g/cm3
Boiling Point 603.4ºC at 760mmHg
Molecular Formula C24H32N4O5
Molecular Weight 456.53500
Flash Point 318.7ºC
Exact Mass 456.23700
PSA 125.97000
LogP 2.97230
Vapour Pressure 1.9E-15mmHg at 25°C
Index of Refraction 1.659

 Synonyms

Lisurida
LISURIDE
3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea
Methylergol Carbamide
Lisuridum
Lysuride
Lysurid