569371-10-4

569371-10-4 structure

Name: UBP301
Chemical Name: UBP 301,(αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoicacid
CAS Number: 569371-10-4
Molecular Formula: C₁₅H₁₄IN₃O₆
Molecular Weight: 459.19300
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2017-10-09 00:50:29
Modify Date: 2024-01-11 11:29:02
UBP301 is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. UBP301 has ∼30-fold selectivity of kainate receptor over AMPA receptor. UBP301 is the derivative of willardiine[1].

Name	UBP 301,(αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoicacid
Synonyms	ubp 301

Description	UBP301 is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. UBP301 has ∼30-fold selectivity of kainate receptor over AMPA receptor. UBP301 is the derivative of willardiine[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	164 μM (kainate receptor)[1]
References	[1]. More JC, et al. Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br J Pharmacol. 2003;138(6):1093-1100.