19395-87-0

19395-87-0 structure
19395-87-0 structure
  • Name: SC 19220
  • Chemical Name: N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
  • CAS Number: 19395-87-0
  • Molecular Formula: C16H14ClN3O3
  • Molecular Weight: 331.754
  • Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
  • Create Date: 2016-07-03 10:00:35
  • Modify Date: 2024-01-21 12:20:29
  • SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis[1][2].

Name N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
Synonyms Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
Lopac-S-3065
N'-Acetyl-8-chlorodibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide
Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
N,N-Dimethylsphingosine
Tocris-1206
8-Chlor-10,11-dihydro-dibenz<b,f><1,4>oxazepin-10-carbonsaeure-N'-acetyl-hydrazid
Description SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis[1][2].
Related Catalog
Target

PGE2[1]

References

[1]. Maggi CA, et al. The effect of SC-19220, a prostaglandin antagonist, on the micturition reflex in rats. Eur J Pharmacol. 1988 Aug 2;152(3):273-9.

[2]. Santangelo S, Shoup M, Gamelli RL, Shankar R. Prostaglandin E2 receptor antagonist (SC-19220) treatment restores the balance to bone marrow myelopoiesis after burn sepsis. J Trauma. 2000 May;48(5):826-30; discussion 830-1.

Density 1.4±0.1 g/cm3
Molecular Formula C16H14ClN3O3
Molecular Weight 331.754
Exact Mass 331.072357
PSA 70.67000
LogP 2.20
Index of Refraction 1.624
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport