SC 19220
SC 19220 structure
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Common Name | SC 19220 | ||
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| CAS Number | 19395-87-0 | Molecular Weight | 331.754 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C16H14ClN3O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of SC 19220SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis[1][2]. |
| Name | N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide |
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| Synonym | More Synonyms |
| Description | SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis[1][2]. |
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| Related Catalog | |
| Target |
PGE2[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
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| Molecular Formula | C16H14ClN3O3 |
| Molecular Weight | 331.754 |
| Exact Mass | 331.072357 |
| PSA | 70.67000 |
| LogP | 2.20 |
| Index of Refraction | 1.624 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats.
Cardiovasc. Res. 78(1) , 130-8, (2008) The present study examined the hypothesis that prostaglandin E2 (PGE2) through activation of prostaglandin E (EP) receptor contributes to endothelium-dependent contractions.Western blotting revealed t... |
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Prostanoid receptors involved in regulation of the beating rate of neonatal rat cardiomyocytes.
PLoS ONE 7(9) , e45273, (2012) Although prostanoids are known to be involved in regulation of the spontaneous beating rate of cultured neonatal rat cardiomyocytes, the various subtypes of prostanoid receptors have not been investig... |
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Prostaglandin E₂ possesses different potencies in inducing Vascular Endothelial Growth Factor and Interleukin-8 production in COPD human lung fibroblasts.
Prostaglandins Leukot. Essent. Fatty Acids 106 , 11-Aug, (2016) We studied the role of PGE2, its biosynthetic enzymes and its receptors, in regulating the functions of lung fibroblasts through the production of Vascular Endothelial Growth Factor (VEGF) and Interle... |
| Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide |
| Lopac-S-3065 |
| N'-Acetyl-8-chlorodibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide |
| Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide |
| N,N-Dimethylsphingosine |
| Tocris-1206 |
| 8-Chlor-10,11-dihydro-dibenz<b,f><1,4>oxazepin-10-carbonsaeure-N'-acetyl-hydrazid |