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  • DC Chemicals Limited
  • China
  • Product Name: CD 1530
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

107430-66-0

107430-66-0 structure
107430-66-0 structure
  • Name: CD 1530
  • Chemical Name: 4-[7-(1-adamantyl)-6-hydroxynaphthalen-2-yl]benzoic acid
  • CAS Number: 107430-66-0
  • Molecular Formula: C27H26O3
  • Molecular Weight: 398.49400
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease RAR/RXR
  • Create Date: 2017-06-30 06:47:22
  • Modify Date: 2024-01-07 19:14:13
  • CD1530 is a selective RARγ agonist with an Kd of 150 nM[1]. CD1530 has been used in combination with bexarotene to inhibit oral carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide in a mouse model of human oral-cavity and esophageal squamous-cell carcinoma[2].

Name 4-[7-(1-adamantyl)-6-hydroxynaphthalen-2-yl]benzoic acid
Synonyms cd 1530
Description CD1530 is a selective RARγ agonist with an Kd of 150 nM[1]. CD1530 has been used in combination with bexarotene to inhibit oral carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide in a mouse model of human oral-cavity and esophageal squamous-cell carcinoma[2].
Related Catalog
Target

RARγ:150 nM (Kd)

References

[1]. Bernard BA, et al. Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor gamma. Biochem Biophys Res Commun. 1992 Jul 31;186(2):977-83.

[2]. Tang XH, et al. Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8907-12.

Density 1.29g/cm3
Boiling Point 610.7ºC at 760 mmHg
Molecular Formula C27H26O3
Molecular Weight 398.49400
Flash Point 337.2ºC
Exact Mass 398.18800
PSA 57.53000
LogP 6.37840
Vapour Pressure 9.03E-16mmHg at 25°C
Index of Refraction 1.688