Name | m40 |
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Synonyms |
GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2
galanin fragment 1-13-pro-pro-ala-*leu-ala-leu-al GALANIN FRAGMENT 1-13-PRO-PRO-ALA-LEU-ALA-LEU-ALA-AMIDE 8-Bromo-cAMP,sodium salt H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2 GWTLNSAGYLLGPPPALALA-NH2 |
Description | M40 is a potent, non-selective galanin receptor antagonist. |
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Related Catalog | |
In Vitro | M40 (1 μM) displaces [mono[125IJodo-Tyr26]galanin from binding sites in the hippocampus, hypothalamus, and spinal cord. M40 has a lower affinity than galanin for all membranes. The IC50 values are 6 nM in the hippocampus, 15 nM in the hypothalamus, 12 nM in the spinal cord, and 3 nM in the insulinoma cells. M40 (1 μM) completely blocks 125I-labeled galanin-binding sites[1]. |
References |
Molecular Formula | C95H146N22O24 |
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Molecular Weight | 1980.31 |
PSA | 715.21000 |
LogP | 2.82290 |
Storage condition | -20°C |