Top Suppliers:I want be here

143896-17-7

143896-17-7 structure
143896-17-7 structure
  • Name: Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amide
  • Chemical Name: m40
  • CAS Number: 143896-17-7
  • Molecular Formula: C95H146N22O24
  • Molecular Weight: 1980.31
  • Catalog: Peptides
  • Create Date: 2018-07-25 21:56:27
  • Modify Date: 2024-01-02 18:39:22
  • M40 is a potent, non-selective galanin receptor antagonist.

Name m40
Synonyms GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2
galanin fragment 1-13-pro-pro-ala-*leu-ala-leu-al
GALANIN FRAGMENT 1-13-PRO-PRO-ALA-LEU-ALA-LEU-ALA-AMIDE
8-Bromo-cAMP,sodium salt
H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2
GWTLNSAGYLLGPPPALALA-NH2
Description M40 is a potent, non-selective galanin receptor antagonist.
Related Catalog
In Vitro M40 (1 μM) displaces [mono[125IJodo-Tyr26]galanin from binding sites in the hippocampus, hypothalamus, and spinal cord. M40 has a lower affinity than galanin for all membranes. The IC50 values are 6 nM in the hippocampus, 15 nM in the hypothalamus, 12 nM in the spinal cord, and 3 nM in the insulinoma cells. M40 (1 μM) completely blocks 125I-labeled galanin-binding sites[1].
References

[1]. Bartfai T, et al. Galanin-receptor ligand M40 peptide distinguishes between putative galanin-receptor subtypes. Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11287-91.

Molecular Formula C95H146N22O24
Molecular Weight 1980.31
PSA 715.21000
LogP 2.82290
Storage condition -20°C