Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amide

Modify Date: 2025-08-31 02:31:41

Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amide structure	Common Name	Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amide
	CAS Number	143896-17-7	Molecular Weight	1980.31
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉₅H₁₄₆N₂₂O₂₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amide

M40 is a potent, non-selective galanin receptor antagonist.

Name	m40
Synonym	More Synonyms

Description	M40 is a potent, non-selective galanin receptor antagonist.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor Peptides Research Areas >> Others
In Vitro	M40 (1 μM) displaces [mono[125IJodo-Tyr26]galanin from binding sites in the hippocampus, hypothalamus, and spinal cord. M40 has a lower affinity than galanin for all membranes. The IC50 values are 6 nM in the hippocampus, 15 nM in the hypothalamus, 12 nM in the spinal cord, and 3 nM in the insulinoma cells. M40 (1 μM) completely blocks 125I-labeled galanin-binding sites[1].
References	[1]. Bartfai T, et al. Galanin-receptor ligand M40 peptide distinguishes between putative galanin-receptor subtypes. Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11287-91.

GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2

galanin fragment 1-13-pro-pro-ala-*leu-ala-leu-al

GALANIN FRAGMENT 1-13-PRO-PRO-ALA-LEU-ALA-LEU-ALA-AMIDE

8-Bromo-cAMP,sodium salt

H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2

GWTLNSAGYLLGPPPALALA-NH2

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Price: $168/500ug