Name | Catalase |
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Synonyms |
4-Hydroxybenzoic acid, ethyl ester
Ethyl 4-hydroxybenzoate Ethyl parasept 4-hydroxybenzoic acid ethyl ester Benzoic acid, 4-hydroxy-, ethyl ester ethyl p-hydroxybenzoate EINECS 232-577-1 Nipagina A Ethyl chemosept Solbrol A MFCD00081483 Ethyl p-oxybenzoate ETHYL PARABEN Ethylparaben |
Description | Catalase is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors[1]. Free oxygen radical scavenger. |
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Related Catalog | |
In Vitro | Catalase, the enzyme that metabolizes H2O2 but also reacts with a multitude of other substrates. The active site of catalase contains an iron atom. Human catalase contains four identical subunits, each subunit containing four distinct domains and one prosthetic heme group. The four domains include: (1) a N-terminal arm which contains a distal histidine, an essential amino acid for the catalase reaction; (2) a β-barrel domain that contains eight β-barrels arranged in an antiparallel fashion with six α-helical insertions, conferring the hydrophobic core of the protein necessary for the tri-dimensional structure of the enzyme; (3) a connection domain which contains the tyrosine residue that binds the heme group; and finally (4) an α-helical domains, which is important for NADPH binding[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 297.5±0.0 °C at 760 mmHg |
Molecular Formula | C9H10O3 |
Molecular Weight | 166.174 |
Flash Point | 120.3±12.6 °C |
Exact Mass | 166.062988 |
LogP | 2.40 |
Appearance | suspension | deep brown |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.539 |
Storage condition | 2-8°C |
Stability | Air and moisture sensitive. Incompatible with strong oxidizing agents. Refrigerate. |
Symbol |
GHS02 |
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Signal Word | Warning |
Hazard Statements | H226 |
Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US);type N95 (US);type P1 (EN143) respirator filter |
Hazard Codes | B |
Risk Phrases | 10 |
Safety Phrases | 23-24/25-22 |
RIDADR | UN 1993 3/PG 3 |
WGK Germany | 1 |
RTECS | FI4378000 |
Hazard Class | 3.0 |