592542-61-5

592542-61-5 structure

Name: (E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Methyl)phenylamino)acetate
Chemical Name: (E)-methyl 2-(2-methoxy-5-((2',4',6'-trimethoxystyrylsulfonyl)methyl)phenylamino)acetate
CAS Number: 592542-61-5
Molecular Formula: C₂₂H₂₇NO₈S
Molecular Weight: 465.51700
Catalog: Research Areas Cancer
Create Date: 2018-07-15 19:13:57
Modify Date: 2024-01-14 23:11:21
Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer[1].

Name	(E)-methyl 2-(2-methoxy-5-((2',4',6'-trimethoxystyrylsulfonyl)methyl)phenylamino)acetate
Synonyms	methyl-{N-[2-methoxy-5-methylene(2',4',6'-trimethoxystyrylsulfonyl)-phenyl]amino}acetate methyl (E)-2-(5-((2,4,6-trimethoxystyrylsulfonyl)methyl)-2-methoxyphenylamino)acetate methyl 2-(5-((2,4,6-trimethoxystyrylsulfonyl)methyl)-2-methoxyphenylamino)acetate (E)-2,4,6-trimethoxystyryl-3-(carbomethoxymethylamino)-4-methoxybenzyl-sulfone (E)-2,4,6-trimethoxystyryl 3-(carbomethoxymethylamno)-4-methoxybenzyl-sulfone

Description	Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Anticancer agent 9 (compound 24) (96 h) inhibits the cell growth, with IC50s of 0.1 μM and 0.1 μM for K562 and DU145 cells, respectively[1].
References	[1]. Pallela VR, et, al. Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910•Na (Rigosertib®), a phase III clinical stage anti-cancer agent. Org Biomol Chem. 2013 Mar 28;11(12):1964-77.