(E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Methyl)phenylamino)acetate

Modify Date: 2024-01-14 23:11:21

(E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Methyl)phenylamino)acetate Structure
(E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Methyl)phenylamino)acetate structure
Common Name (E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Methyl)phenylamino)acetate
CAS Number 592542-61-5 Molecular Weight 465.51700
Density N/A Boiling Point N/A
Molecular Formula C22H27NO8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Methyl)phenylamino)acetate


Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer[1].

 Names

Name (E)-methyl 2-(2-methoxy-5-((2',4',6'-trimethoxystyrylsulfonyl)methyl)phenylamino)acetate
Synonym More Synonyms

  Biological Activity

Description Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer[1].
Related Catalog
In Vitro Anticancer agent 9 (compound 24) (96 h) inhibits the cell growth, with IC50s of 0.1 μM and 0.1 μM for K562 and DU145 cells, respectively[1].
References

[1]. Pallela VR, et, al. Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910•Na (Rigosertib®), a phase III clinical stage anti-cancer agent. Org Biomol Chem. 2013 Mar 28;11(12):1964-77.

 Chemical & Physical Properties

Molecular Formula C22H27NO8S
Molecular Weight 465.51700
Exact Mass 465.14600
PSA 117.77000
LogP 4.04540

 Synonyms

methyl-{N-[2-methoxy-5-methylene(2',4',6'-trimethoxystyrylsulfonyl)-phenyl]amino}acetate
methyl (E)-2-(5-((2,4,6-trimethoxystyrylsulfonyl)methyl)-2-methoxyphenylamino)acetate
methyl 2-(5-((2,4,6-trimethoxystyrylsulfonyl)methyl)-2-methoxyphenylamino)acetate
(E)-2,4,6-trimethoxystyryl-3-(carbomethoxymethylamino)-4-methoxybenzyl-sulfone
(E)-2,4,6-trimethoxystyryl 3-(carbomethoxymethylamno)-4-methoxybenzyl-sulfone
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