Name | N-(Prop-2-ynyl)biotinamide |
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Synonyms |
Biotin propargylamide, 3-(D-Biotinylamido)-1-propyne, Prop-2-ynylamide biotin
5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(prop-2-ynyl)pentanamide |
Description | Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.185±0.06 g/cm3(Predicted) |
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Boiling Point | 614.8±50.0 °C(Predicted) |
Melting Point | 169-170 °C |
Molecular Formula | C13H19N3O2S |
Molecular Weight | 281.37400 |
Exact Mass | 281.12000 |
PSA | 95.53000 |
LogP | 1.51010 |
Hazard Codes | Xi |
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