9014-01-1

9014-01-1 structure

Name: Subtilisin (Compound proteinase)
Chemical Name: Casein
CAS Number: 9014-01-1
Molecular Formula: C₁₁H₉N₃O_2.Na
Molecular Weight: 238.19786
Catalog: Food additive Enzyme
Create Date: 2018-02-07 08:00:00
Modify Date: 2024-01-04 22:45:15
Subtilisin Compound proteinase (Protamex) is a proteolytic enzyme. Subtilisin Compound proteinase has catalytic activity in anhydrous dimethyl formamide. Subtilisin Compound proteinase can be used as a catalyst for easy coupling between sugars and amino acids[1][2].

Name	Casein
Synonyms	MFCD00132092 EINECS 232-752-2

Description	Subtilisin Compound proteinase (Protamex) is a proteolytic enzyme. Subtilisin Compound proteinase has catalytic activity in anhydrous dimethyl formamide. Subtilisin Compound proteinase can be used as a catalyst for easy coupling between sugars and amino acids[1][2].
Related Catalog	Research Areas >> Others
In Vitro	Subtilisin Compound proteinase 在二甲基甲酰胺中选择性的酰化二糖、寡糖、核苷和相关的大分子[1]。 Subtilisin Compound proteinase 在活化的丁酸三氟乙酯 (TFEB) 存在下，可以酰化黄烷醇异槲皮素 (1) 的 D-葡萄糖[3]。 Subtilisin Compound proteinase 改善了蛋白质和脂肪酸的溶解度，恢复了多肽和不饱和脂肪酸[4]。
In Vivo	Subtilisin Compound proteinase 水解产物 (150 mg/kg 和 300 mg/kg；口服；一天一次持续 6 周) (≤1 kDa 的葡糖乳蛋白水解物，MLPH) 对 ob/ob 小鼠具有抗肥胖和抗高血糖作用[4]。
References	[1]. Riva S, et al. Protease-catalyzed regioselective esterification of sugars and related compounds in anhydrous dimethylformamide[J]. Journal of the American Chemical Society, 1988, 110(2): 584-589. [2]. Philipp M, et al. Inhibition of subtilisin by substituted arylboronic acids. FEBS Lett. 1981 Oct 12;133(1):36-8. [3]. Danieli B, et al. On the regioselectivity of the protease subtilisin towards the acylation of enantiomeric pairs of benzyl and naphthyl glycopyranosides. Part 2[J]. Tetrahedron, 1999, 55(7): 2045-2060. [4]. Kim MJ, et al. Anti-Obesity and Anti-Hyperglycemic Effects of Meretrix lusoria Protamex Hydrolysate in ob/ob Mice. Int J Mol Sci. 2022 Apr 5;23(7):4015.

Density	1.3
Molecular Formula	C₁₁H₉N₃O_2.Na
Molecular Weight	238.19786
Appearance	powder \| white
Storage condition	2-8°C
Stability	store cold

Symbol	GHS05, GHS07, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H302-H315-H318-H334-H335-H410
Precautionary Statements	P261-P273-P280-P305 + P351 + P338-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn,N
Risk Phrases	37/38-41-42-36/37/38-50-22
Safety Phrases	23-24-26-36/37/39-22-36/37-61-45-39
RIDADR	3082
WGK Germany	2
RTECS	UK9540000
HS Code	35079090

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