374796-72-2
374796-72-2 structure
- Name: (Asn23)-Amyloid β-Protein (1-40)
- Chemical Name: (Asn23)-Amyloid beta-Protein (1-40)
- CAS Number: 374796-72-2
- Molecular Formula: C194H296N54O57S
- Molecular Weight:
- Catalog: Research Areas Others
- Create Date: 2016-03-27 15:34:45
- Modify Date: 2024-02-19 10:09:29
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[Asn23] β-Amyloid (1-40), Iowa mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA). The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.)
| Name | (Asn23)-Amyloid beta-Protein (1-40) |
|---|---|
| Synonyms | (Asn7)-Amyloid β-Protein (1-40) |
| Description | [Asn23] β-Amyloid (1-40), Iowa mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA). The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.) |
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| Related Catalog |
| Molecular Formula | C194H296N54O57S |
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