1013933-37-3

1013933-37-3 structure

Name: CP 376395 hydrochloride
Chemical Name: CP-376395 hydrochloride
CAS Number: 1013933-37-3
Molecular Formula: C₂₁H₃₁ClN₂O
Molecular Weight: 362.94
Catalog: Signaling Pathways GPCR/G Protein CRFR
Create Date: 2018-01-20 08:37:22
Modify Date: 2024-01-12 11:53:15
CP 376395 hydrochloride is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist[1][2].

Name	CP-376395 hydrochloride
Synonyms	Remoxipride hydrochloride

Description	CP 376395 hydrochloride is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> CRFR Research Areas >> Neurological Disease
Target	CRFR1 CRFR2
References	[1]. Chen YL, et al. 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists. J Med Chem. 2008 Mar 13;51(5):1385-92. [2]. Giardino WJ, et al. CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption. Alcohol Clin Exp Res. 2013 Jul;37(7):1161-70.