1172605-58-1

1172605-58-1 structure

Name: Fmoc-N-amido-PEG3-azide
Chemical Name: 1-(Fmoc-amino)-11-azido-3,6,9-trioxaundecane
CAS Number: 1172605-58-1
Molecular Formula: C₂₃H₂₈N₄O₅
Molecular Weight: 440.49200
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-01-20 13:03:37
Modify Date: 2024-01-09 07:57:42
Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-(Fmoc-amino)-11-azido-3,6,9-trioxaundecane

Description	Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562