Fmoc-N-amido-PEG3-azide

Modify Date: 2024-01-09 07:57:42

Fmoc-N-amido-PEG3-azide Structure
Fmoc-N-amido-PEG3-azide structure
Common Name Fmoc-N-amido-PEG3-azide
CAS Number 1172605-58-1 Molecular Weight 440.49200
Density N/A Boiling Point N/A
Molecular Formula C23H28N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-N-amido-PEG3-azide


Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-(Fmoc-amino)-11-azido-3,6,9-trioxaundecane

 Fmoc-N-amido-PEG3-azide Biological Activity

Description Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C23H28N4O5
Molecular Weight 440.49200
Exact Mass 440.20600
PSA 115.77000
LogP 3.72886