96156-26-2

96156-26-2 structure

Name: Displurigen
Chemical Name: 8-hydroxy-2-phenyl-4H-thiochromen-4-one 1,1-dioxide
CAS Number: 96156-26-2
Molecular Formula: C₁₅H₁₀O₄S
Molecular Weight: 286.30300
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2018-05-10 00:25:08
Modify Date: 2024-01-12 16:11:55
Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC50 = 225 μM)[1].

Name	8-hydroxy-2-phenyl-4H-thiochromen-4-one 1,1-dioxide

Description	Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC50 = 225 μM)[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
References	[1]. Yijie Geng, et al. A Chemical Biology Study of Human Pluripotent Stem Cells Unveils HSPA8 as a Key Regulator of Pluripotency. Stem Cell Reports. 2015 Dec 8;5(6):1143-1154.