230620-75-4

230620-75-4 structure

Name: Benzyl-PEG7-THP
Chemical Name: 1-benzyl-22-(tetrahydropyranyl) heptaethylene glycol
CAS Number: 230620-75-4
Molecular Formula: C₂₆H₄₄O₉
Molecular Weight: 500.62200
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-04-06 03:09:52
Modify Date: 2024-01-10 10:43:36
Benzyl-PEG7-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-benzyl-22-(tetrahydropyranyl) heptaethylene glycol

Description	Benzyl-PEG7-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562