Benzyl-PEG7-THP

Modify Date: 2024-01-10 10:43:36

Benzyl-PEG7-THP Structure
Benzyl-PEG7-THP structure
Common Name Benzyl-PEG7-THP
CAS Number 230620-75-4 Molecular Weight 500.62200
Density N/A Boiling Point N/A
Molecular Formula C26H44O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyl-PEG7-THP


Benzyl-PEG7-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-benzyl-22-(tetrahydropyranyl) heptaethylene glycol

 Benzyl-PEG7-THP Biological Activity

Description Benzyl-PEG7-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H44O9
Molecular Weight 500.62200
Exact Mass 500.29900
PSA 83.07000
LogP 2.84600