52190-55-3

52190-55-3 structure

Name: m-PEG4-SH
Chemical Name: 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol
CAS Number: 52190-55-3
Molecular Formula: C₉H₂₀O₄S
Molecular Weight: 224.31800
Catalog: Chemical reagent Organic reagent Thiol salt
Create Date: 2018-12-26 22:07:27
Modify Date: 2026-08-06 10:52:25
m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanethiol
Synonyms	m-PEG-4-SH,Inhibitor,m PEG4 SH,PROTAC Linkers,mPEG4SH,inhibit m-dPEG-Thiol MPEG4-HS m-PEG4-thiol Me-PEG4-SH 2,5,8,11-TETRAOXATRIDECANE-13-THIOL m-dPEG-Thiol (QBD-10792) 3,6,9,12-Tetraoxatridecane-1-thiol mPEG4-SH/2,5,8,11-Tetraoxatridecane-13-thiol Thiol-PEG4-methyl MPEG4-SH

Description	m-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.