155836-50-3

155836-50-3 structure

Name: BW 373U86
Chemical Name: (+)bw373u86
CAS Number: 155836-50-3
Molecular Formula: C₂₇H₃₇N₃O₂
Molecular Weight: 435.60
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2018-02-12 00:53:45
Modify Date: 2024-01-08 19:40:30
BW373U86 (SNC86) is a δ-opioid receptor agonist with an IC50 of 1.49 nM. BW373U86 shows antidepressant-like effects[1].

Name	(+)bw373u86
Synonyms	SNC 86 (+)-4-[α(R)-α-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-hydroxyphenyl)methyl]-N,N-diethylbenzamide (+)-BW373U86 SNC86 4-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide BW373486

Description	BW373U86 (SNC86) is a δ-opioid receptor agonist with an IC50 of 1.49 nM. BW373U86 shows antidepressant-like effects[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	IC50: 1.49 nM (δ-opioid receptor)[1]
References	[1]. Jutkiewicz EM, et al. Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats. J Pharmacol Exp Ther. 2004 Apr;309(1):173-81.