134-46-3

134-46-3 structure

Name: Fluorodeoxyuridylate
Chemical Name: 5-fluoro-2'-deoxyuridylic acid
CAS Number: 134-46-3
Molecular Formula: C₂₁H₄₂FN₄O₈P
Molecular Weight: 528.55
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-02-18 10:48:10
Modify Date: 2024-01-17 01:18:25
2’-Deoxy-5-Fluorouridine 5’-phosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-fluoro-2'-deoxyuridylic acid
Synonyms	5-F-dUMP FdUMP 5-fluoro-2'-deoxyuridine monophosphate 5-fluoro-2'-deoxyuridine-5'-O-monophosphate 5-fluoro-2'-deoxyuridine-5'-monophosphate 5-fluoro-2'-deoxyuridine 5'-monophosphate

Description	2’-Deoxy-5-Fluorouridine 5’-phosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.