Fluorodeoxyuridylate

Modify Date: 2024-01-17 01:18:25

Fluorodeoxyuridylate Structure
Fluorodeoxyuridylate structure
Common Name Fluorodeoxyuridylate
CAS Number 134-46-3 Molecular Weight 528.55
Density N/A Boiling Point N/A
Molecular Formula C21H42FN4O8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fluorodeoxyuridylate


2’-Deoxy-5-Fluorouridine 5’-phosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-fluoro-2'-deoxyuridylic acid
Synonym More Synonyms

 Fluorodeoxyuridylate Biological Activity

Description 2’-Deoxy-5-Fluorouridine 5’-phosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C21H42FN4O8P
Molecular Weight 528.55
Exact Mass 326.03200
PSA 160.89000

 Synonyms

5-F-dUMP
FdUMP
5-fluoro-2'-deoxyuridine monophosphate
5-fluoro-2'-deoxyuridine-5'-O-monophosphate
5-fluoro-2'-deoxyuridine-5'-monophosphate
5-fluoro-2'-deoxyuridine 5'-monophosphate