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139115-89-2

139115-89-2 structure
139115-89-2 structure
  • Name: Hydroxy-PEG3-MS
  • Chemical Name: 2-(2-(2-((Methanesulfonyl)oxy)ethoxy)ethoxy)ethanol
  • CAS Number: 139115-89-2
  • Molecular Formula: C7H16O6S
  • Molecular Weight: 228.26300
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-26 16:34:56
  • Modify Date: 2024-01-02 10:31:23
  • Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-(2-(2-((Methanesulfonyl)oxy)ethoxy)ethoxy)ethanol
Synonyms 2-(2-(2-hydroxyethoxy)ethoxy)ethyl methanesulfonate
8-hydroxy-3,6-dioxaoctyl methanesulphonate
triethylene glycol
Hydroxy-PEG3-MS
Description Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C7H16O6S
Molecular Weight 228.26300
Exact Mass 228.06700
PSA 90.44000
LogP 0.06890