Hydroxy-PEG3-MS

Modify Date: 2024-01-02 10:31:23

Hydroxy-PEG3-MS Structure
Hydroxy-PEG3-MS structure
Common Name Hydroxy-PEG3-MS
CAS Number 139115-89-2 Molecular Weight 228.26300
Density N/A Boiling Point N/A
Molecular Formula C7H16O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG3-MS


Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-(2-((Methanesulfonyl)oxy)ethoxy)ethoxy)ethanol
Synonym More Synonyms

 Hydroxy-PEG3-MS Biological Activity

Description Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C7H16O6S
Molecular Weight 228.26300
Exact Mass 228.06700
PSA 90.44000
LogP 0.06890

 Synonyms

2-(2-(2-hydroxyethoxy)ethoxy)ethyl methanesulfonate
8-hydroxy-3,6-dioxaoctyl methanesulphonate
triethylene glycol
Hydroxy-PEG3-MS