| Name | N-BOC-Diethanolamine |
|---|---|
| Synonyms |
MFCD01862953
N-Boc-diethanolamine tert-Butyl bis(2-hydroxyethyl)carbamate TERT-BUTYL N,N-BIS(2-HYDROXYETHYL)CARBAMATE |
| Description | N-Boc-diethanolamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.085 |
|---|---|
| Boiling Point | 324.2ºC at 760 mmHg |
| Molecular Formula | C9H19NO4 |
| Molecular Weight | 205.25100 |
| Flash Point | 149.9ºC |
| Exact Mass | 205.13100 |
| PSA | 70.00000 |
| LogP | 0.20810 |
| Appearance | Liquid or Oil | Colorless |
| Vapour Pressure | 1.95E-05mmHg at 25°C |
| Index of Refraction | 1.46 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2924199090 |
|
~98%
103898-11-9 |
| Literature: Donaldson, Susan F.; Bergmeier, Stephen C.; Hines, Jennifer V.; Gerdeman, Melinda S. Nucleosides, Nucleotides and Nucleic Acids, 2002 , vol. 21, # 2 p. 111 - 123 |
|
~%
103898-11-9 |
| Literature: US4987130 A1, ; |
| Precursor 3 | |
|---|---|
| DownStream 2 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |