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112018-01-6

112018-01-6 structure
112018-01-6 structure

Name 6 (3,4 dihydro 3 oxo 2h 1,4 benzoxazin 7 yl) 2,3,4,5 tetrahydro 5 methyl 3 pyridazinone
Synonyms 6-[3,4-dihydro-3-oxo-1,4(2H)-benzoxazin-7-yl]-2,3,4,5-tetrahydro-5-methylpyridazin-3-one
bemoradan
bemorandan
6-(3,4-dihydro-3-oxo-1,4(2H)-benzoxazin-7-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one
RWJ 22867
Description Bemoradan (compound 10a) is an orally active and selective canine Phosphodiesterase (PDE) fraction III inhibitor. Bemoradan is a long-acting, potent, inotropic vasodilator and a novel cardiotonic agent, and can be used in congestive heart failure research[1].
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References

[1]. Combs DW, et al. 6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents. J Med Chem. 1990 Jan;33(1):380-6.  

Molecular Formula C13H13N3O3
Molecular Weight 259.26
Exact Mass 259.09600
PSA 79.79000
LogP 0.78000
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