65429-42-7
65429-42-7 structure
- Name: (6A,11B,16A,17A)-6,9-DIFLUORO-11-HYDROXY-16-METHYL-3-OXO-17-(1-OXOPROPOXY)ANDROSTA-1,4-DIENE-17-CARBOXYLIC ACID
- Chemical Name: (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid
- CAS Number: 65429-42-7
- Molecular Formula: C24H30F2O6
- Molecular Weight: 452.48800
- Create Date: 2019-01-08 20:28:00
- Modify Date: 2026-08-02 15:41:29
| Name | (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid |
|---|---|
| Synonyms |
Fluticasone 17β-Cboxylic Acid Propionate
Fluticasone Propionate Impurity A/Fluticasone Cboxylic Acid Propionate/6α,9-difluoro-11β-hydroxy-16α-methyl-3-oxo-17-(propanoyloxy) androsta-1,4-diene-17β-cboxylic acid Androsta-1,4-diene-17- cboxylic acid, 6,9-difluoro-11- hydroxy-16-Methyl-3-oxo-17-(1-oxopropoxy)-,(6α,11β,16α,17α) 6α,9α- Difluoro-11 β- Hydroxy-16 α- Methyl-3-oxo-17 α- (1-propionyl) androsterol-1,4-diene-17 β- formic acid 6alpha,9-Difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17-(propanoyloxy)androsta-1,4-diene-17beta-c Fluticasone Imp A (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-cboxylic Acid 6α,9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)androsta-1,4-diene-17β-cboxylic acid UNII-TP537C010A Flutione 17|A-Carboxylic Acid Propionate Fluticasone Impurity A (Fluticasone Cboxylic Acid Propionate) 6a,9a-difluoro-l1~-hydroxy-l6a-methyl-l7apropionyloxy-3-oxoandrosta-l,4-diene-l7~-cboxyliacc id 6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-cboxylic acid 6α,9-difluoro-11β-hydroxy-16α-methyl-3-oxo-17-(propanoyloxy) androsta-1,4-diene-17β-cboxylic acid Fluticasone Impurity 1(Fluticasone Impurity A) (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(propio (Fluticasone Propionate Impurity) Fluticasone IMpurity A (6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17 (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxo-propoxy)androsta-1,4-diene-17-cboxylic acid Fluticasone Propinate impurity A -I Fluticasone Propionate Impurity fluticasone propionate impurity -ZA "6α,9-difluoro-11β-hydroxy-16α-methyl-3-oxo-17- (propanoyloxy)androsta-14-diene-17β-cboxylic acid 6α, 9α-Difluoro-11β-Hydroxy-16α-methyl-3-oxo-17α-(1-oxopropyloxy) androstene-1,4-diene-17β-formic acid 6alpha,9-Difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17-(propanoyloxy)androsta-1,4-diene-17beta-cboxylic Acid Fluticasone Propionate Impurity A Flutione propionate-17beta-carboxylic acid BNKY011-FP02 FLUTICASONE PROPIONATE, 17-BETA CBOXYLIC ACID (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-cboxylic acid (6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-cboxylic acid Fluticasone Propinate impurity A Fluticasone 17beta-Cboxylic Acid Propionate Flutione 17beta-carboxylic acid |
| Density | 1.33 |
|---|---|
| Boiling Point | 577.645ºC at 760 mmHg |
| Molecular Formula | C24H30F2O6 |
| Molecular Weight | 452.48800 |
| Flash Point | 303.149ºC |
| Exact Mass | 452.20100 |
| PSA | 100.90000 |
| LogP | 3.32780 |
| Index of Refraction | 1.561 |
| Storage condition | -20°C |
|
~97%
65429-42-7 |
| Literature: Alpharma APS Patent: EP1466920 A1, 2004 ; Location in patent: Page 7 ; |
|
~99%
65429-42-7 |
| Literature: SUN PHARMACEUTICAL INDUSTRIES LIMITED Patent: US2005/256325 A1, 2005 ; Location in patent: Page/Page column 8 ; |
|
Detail
|
| Literature: Barkalow, Jufang; Chamberlin, Steven A.; Cooper, Arthur J.; Hossain, Azad; Hufnagel, John J.; Langridge, Denton Patent: US2002/133032 A1, 2002 ; |
|
~%
65429-42-7 |
| Literature: Journal of Organic Chemistry, , vol. 51, # 12 p. 2315 - 2328 |
| Precursor 7 | |
|---|---|
| DownStream 4 | |
