1162336-72-2

1162336-72-2 structure
1162336-72-2 structure
  • Name: Azido-C1-PEG3-C3-NH2
  • Chemical Name: 3-(2-(2-(3-azidopropoxy)ethoxy)ethoxy)propan-1-amine
  • CAS Number: 1162336-72-2
  • Molecular Formula: C10H22N4O3
  • Molecular Weight: 246.30700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-05-14 02:02:53
  • Modify Date: 2024-01-09 16:00:54
  • Azido-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3-(2-(2-(3-azidopropoxy)ethoxy)ethoxy)propan-1-amine
Synonyms n3-tota 1-azido-4,7,10-trioxa-13-tridecanamine
Description Azido-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H22N4O3
Molecular Weight 246.30700
Exact Mass 246.16900
PSA 103.46000
LogP 1.23846
Hazard Codes Xi