1478364-68-9

1478364-68-9 structure

Name: PXS-4728A
Chemical Name: pxs-4728
CAS Number: 1478364-68-9
Molecular Formula: C₁₅H₂₂ClFN₂O₂
Molecular Weight: 316.79900
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2018-06-29 23:46:44
Modify Date: 2024-01-10 06:40:00
PXS-4728A is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO). PXS-4728A ameliorates chronic obstructive pulmonary disease in mice[1].

Name	pxs-4728
Synonyms	PXS-4728A (E)-4-((2-(aminomethyl)-3-fluoroallyl)oxy)-N-(tert-butyl)benzamide hydrochloride Benzamide, 4-(((2E)-2-(aminomethyl)-3-fluoro-2-propen-1-yl)oxy)-N-(1,1-dimethylethyl)-, hydrochloride (1:1)

Description	PXS-4728A is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO). PXS-4728A ameliorates chronic obstructive pulmonary disease in mice[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Inflammation/Immunology
Target	SSAO[1]
References	[1]. A G Jarnicki, et al. The Inhibitor of Semicarbazide-Sensitive Amine Oxidase, PXS-4728A, Ameliorates Key Features of Chronic Obstructive Pulmonary Disease in a Mouse Model. Br J Pharmacol. 2016 Nov;173(22):3161-3175.