Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5-AMINOTROPOLONE
Price:
Purity: 97.0%
Stocking Period: 10 Day
Contact: Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-AMINOTROPOLONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

7021-46-7

7021-46-7 structure

Name: 5-AMINOTROPOLONE
Chemical Name: 5-amino-2-hydroxycyclohepta-2,4,6-trien-1-one
CAS Number: 7021-46-7
Molecular Formula: C₇H₇NO₂
Molecular Weight: 137.13600
Create Date: 2017-08-16 04:03:16
Modify Date: 2024-01-16 08:57:52

Name	5-amino-2-hydroxycyclohepta-2,4,6-trien-1-one
Synonyms	2,4,6-CYCLOHEPTATRIEN-1-ONE,5-AMINO-2-HYDROXY VII tropolone 5-amino-2-hydroxytropone 5-aminotopolone 5-amino-tropolone 5-Amino-2-hydroxy-2,4,6-cycloheptatrien-1-one 5-Amino-tropolon

Density	1.356g/cm3
Boiling Point	262.3ºC at 760 mmHg
Molecular Formula	C₇H₇NO₂
Molecular Weight	137.13600
Flash Point	112.5ºC
Exact Mass	137.04800
PSA	63.32000
LogP	0.91580
Index of Refraction	1.638

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU3829500

CHEMICAL NAME :: 2,4,6-Cycloheptatrien-1-one, 5-amino-2-hydroxy-

CAS REGISTRY NUMBER :: 7021-46-7

BEILSTEIN REFERENCE NO. :: 1524779

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H7-N-O2

MOLECULAR WEIGHT :: 137.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 230 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - analgesia Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 91,550,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 521 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - analgesia Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 91,550,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 92,19,1972

2297-94-1

~94%

7021-46-7

Literature: Research Foundation Itsuu Laboratory Patent: EP1357104 A1, 2003 ; Location in patent: Page/Page column 6-7 ;

533-75-5

7021-46-7

Literature: Potenziano, James; Spitale, Robert; Janik, Mark E. Synthetic Communications, 2005 , vol. 35, # 15 p. 2005 - 2016

82968-90-9

~0%

7021-46-7

22057-97-2

Literature: Yamamoto, Hiroshi; Hara, Atsushi; Noguchi, Ayashi; Kawamoto, Heizan; Inokawa, Saburo; Nozoe, Tetsuo Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 5 p. 1594 - 1598

2297-94-1

7772-99-8

~10%

7021-46-7

Literature: Luminex Corporation Patent: US7867774 B2, 2011 ;

82968-89-6

7021-46-7

22057-97-2

Literature: Yamamoto, Hiroshi; Hara, Atsushi; Noguchi, Ayashi; Kawamoto, Heizan; Inokawa, Saburo; Nozoe, Tetsuo Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 5 p. 1594 - 1598

82968-90-9

7021-46-7

Literature: Yamamoto, Hiroshi; Hara, Atsushi; Noguchi, Ayashi; Kawamoto, Heizan; Inokawa, Saburo; Nozoe, Tetsuo Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 5 p. 1594 - 1598

33655-58-2

7021-46-7

Literature: Kato,M. et al. Tetrahedron, 1971 , vol. 27, p. 4013 - 4020

21578-78-9

7021-46-7

Literature: Sunagawa,G.; Watatani,M. Chemical and Pharmaceutical Bulletin, 1968 , vol. 16, # 7 p. 1308 - 1315

67-56-1

52003-24-4

7021-46-7

Literature: Nozoe et al. Sci. Rep. Tohoku Univ., Ser. 1: Phys., Chem., Astron., 1952 , vol. # 35, p. 1895,274,281

Precursor 7
2297-94-1 533-75-5 82968-90-9 7772-99-8
82968-89-6 33655-58-2 67-56-1
DownStream 2
3172-00-7 60423-21-4

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