518044-32-1

518044-32-1 structure

Name: Hydroxy-PEG4-(CH2)2-Boc
Chemical Name: tert-butyl 3-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)propanoate
CAS Number: 518044-32-1
Molecular Formula: C₁₅H₃₀O₇
Molecular Weight: 322.39500
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-05-15 07:40:41
Modify Date: 2024-01-03 10:28:11
Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191).

Name	tert-butyl 3-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)propanoate
Synonyms	tert-butyl 3-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]propanoate tert-butyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate tert-butyl 15-hydroxy-4,7,10,13-tetraoxapentadecanoate tert-butyl-15-hydroxy-4,7,10,13-tetraoxapentadecanoate t-butyl 15-hydroxy-4,7,10,13-tetraoxapentadecanoate 15-Hydroxy-4,7,10,13-tetraoxapentadecanoic acid tert-butyl ester

Description	Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2.