52386-42-2

52386-42-2 structure

Name: Emofolin sodium
Chemical Name: L-Glutamic acid, N-[4-[[2-(2-amino-1,4,5,6,7,8-hexahydro- 5-methyl-4-oxo-6-pteridinyl)ethyl]amino]benzoyl]-, disodium salt
CAS Number: 52386-42-2
Molecular Formula: C₂₁H₂₇N₇O₆
Molecular Weight: 473.48200
Catalog: Signaling Pathways Cell Cycle/DNA Damage Antifolate
Create Date: 2018-09-09 18:07:00
Modify Date: 2024-01-03 01:08:31
Ketotrexate sodium is an orally active antifolate and immunosuppressant. Ketotrexate sodium has good anti-inflammatory activity and is widely used in rheumatoid arthritis (RA). Ketotrexate sodium is used in research into cancer and autoimmune diseases[1][2].

Name	L-Glutamic acid, N-[4-[[2-(2-amino-1,4,5,6,7,8-hexahydro- 5-methyl-4-oxo-6-pteridinyl)ethyl]amino]benzoyl]-, disodium salt

Description	Ketotrexate sodium is an orally active antifolate and immunosuppressant. Ketotrexate sodium has good anti-inflammatory activity and is widely used in rheumatoid arthritis (RA). Ketotrexate sodium is used in research into cancer and autoimmune diseases[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Antifolate Research Areas >> Inflammation/Immunology
References	[1]. Puig L. Methotrexate: new therapeutic approaches. Actas Dermosifiliogr. 2014 Jul-Aug;105(6):583-9. [2]. Torres RP, et al. Methotrexate: Implications of pharmacogenetics in the treatment of patients with Rheumatoid Arthritis. ARP Rheumatol. 2022 Oct 1;1(3):225-229.