209984-58-7

209984-58-7 structure

Name: LY-411575 (isomer 1)
Chemical Name: N2-((2R)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-L-alaninamide
CAS Number: 209984-58-7
Molecular Formula: C₂₆H₂₃F₂N₃O₄
Molecular Weight: 479.47500
Catalog: Signaling Pathways Neuronal Signaling γ-secretase
Create Date: 2018-02-03 08:10:00
Modify Date: 2026-07-01 13:32:32
LY-411575 isomer 1 is an isomer of LY411575, which is a potent γ-secretase inhibitor.

Name	N2-((2R)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-L-alaninamide
Synonyms	Benzeneacetamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-α-hydroxy-, (αR) (S)-2-((R)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azin-7-yl)propanamide LY-411575 (isoMer 1) LY411575 isomer 1,LY 411575 isomer 1

Description	LY-411575 isomer 1 is an isomer of LY411575, which is a potent γ-secretase inhibitor.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> γ-secretase Signaling Pathways >> Stem Cell/Wnt >> γ-secretase Research Areas >> Neurological Disease
References	[1]. Fauq AH, et al. A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6392-5. Epub 2007 Aug 30.