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89845-82-9

89845-82-9 structure
89845-82-9 structure
  • Name: 2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
  • Chemical Name: 2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
  • CAS Number: 89845-82-9
  • Molecular Formula: C17H25N3O5S
  • Molecular Weight: 383.46
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2018-05-05 05:53:21
  • Modify Date: 2024-02-05 10:46:12
  • 2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
Synonyms 1-((3aR,4R,6R,6aR)-6-Hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-5-pyrrolidin-1-ylmethyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
Description 2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Molecular Formula C17H25N3O5S
Molecular Weight 383.46
Exact Mass 383.15100
PSA 121.04000
LogP 0.84940