2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine

Modify Date: 2024-02-05 10:46:12

2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine Structure
2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine structure
Common Name 2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
CAS Number 89845-82-9 Molecular Weight 383.46
Density N/A Boiling Point N/A
Molecular Formula C17H25N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine


2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
Synonym More Synonyms

  Biological Activity

Description 2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C17H25N3O5S
Molecular Weight 383.46
Exact Mass 383.15100
PSA 121.04000
LogP 0.84940

 Synonyms

1-((3aR,4R,6R,6aR)-6-Hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-5-pyrrolidin-1-ylmethyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one