40013-87-4

40013-87-4 structure

Name: 24 25-Dihydroxy VD3
Chemical Name: 24,25-Dihydroxyvitamin D3
CAS Number: 40013-87-4
Molecular Formula: C₂₇H₄₄O₃
Molecular Weight: 416.63600
Catalog: Signaling Pathways Vitamin D Related VD/VDR
Create Date: 2018-02-06 08:00:00
Modify Date: 2025-08-25 18:55:34
24, 25-Dihydroxy VD3 is a compound which is closely related to 1,25-dihydroxyvitamin D3, the active form of vitamin D3, but like vitamin D3 itself and 25-hydroxyvitamin D3 is inactive as a hormone both in vitro and in vivo.

Name	24,25-Dihydroxyvitamin D3
Synonyms	24R,25-dihydroxycholecalciferol 24,25 dihydroxycholecalciferol 24,25-dihydroxyvitamin D3 24,25-dihydroxycholecalciferol 24,25-dihydroxy-vitamin D3 (R)-6-{(1R,3aS,7aR)-4-[2-[(S)-5-Hydroxy-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-2-methyl-heptane-2,3-diol 24, 25-Dihydroxy VD3

Description	24, 25-Dihydroxy VD3 is a compound which is closely related to 1,25-dihydroxyvitamin D3, the active form of vitamin D3, but like vitamin D3 itself and 25-hydroxyvitamin D3 is inactive as a hormone both in vitro and in vivo.
Related Catalog	Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Metabolic Disease Natural Products >> Others
Target	Human Endogenous Metabolite
References	[1]. Takayama H.Creation of functional organic compounds and their applicationsYakugaku Zasshi. 2002 Feb;122(2):127-55. [2]. Kim YR, Abraham NG, Lutton JD.Mechanisms of differentiation of U937 leukemic cells induced by GM-CSF and 1,25(OH)2 vitamin D3.Leuk Res. 1991;15(6):409-18. [3]. Dennis Wagner, Heather E. Hanwell, Kareena Schnabl et al. The ratio of serum 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 is predictive of 25-hydroxyvitamin D3 response to vitamin D3 supplementation. The Journal of Steroid Biochemistry and Molecular Biology.Volume 126, Issues 3-5, September 2011, Pages 72-77