120555-31-9

120555-31-9 structure

Name: Ro-24-0238
Chemical Name: Ro 24-0238
CAS Number: 120555-31-9
Molecular Formula: C₂₇H₃₆N₂O₂
Molecular Weight: 420.58700
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-03-10 05:55:58
Modify Date: 2024-01-09 22:15:04
Ro-24-0238 is an antagonist of platelet activating factor (PAF) and inhibitor of thromboxane synthesis, used for lessening the inflammation and damage resulting from a local release of PAF.

Name	Ro 24-0238
Synonyms	(R)-(2E,4E)-5-(4-methoxyphenyl)-N-[1-methyl-4-(3-pyridinyl)butyl]-2,4-decadienamide [R-(E,E)]-5-(4-methoxyphenyl)-N-[1-methyl-4-(3-pyridinyl)butyl]-2.4-decadienamide (2E,4E)-5-(4-Methoxy-phenyl)-deca-2,4-dienoic acid ((R)-1-methyl-4-pyridin-3-yl-butyl)-amide <R-(E,E)>-5-(4-methoxyphenyl)-N-<1-methyl-4-(3-pyridinyl)butyl>-2,4-decadienamide (R-(E,E))-5-(4-methoxyphenyl)-N-[1-methyl-4-(3-pyridinyl)butyl]-2,4-decadienamide Ro-24-0238

Description	Ro-24-0238 is an antagonist of platelet activating factor (PAF) and inhibitor of thromboxane synthesis, used for lessening the inflammation and damage resulting from a local release of PAF.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	Pretreatment with 3 mg/kg Ro 24-0238 and 3 mg/kg WEB 2086 decreases the accumulation of neutrophils within the mucosa in rats[1].
References	[1]. Will PC, et al. Platelet activating factor as a proinflammatory mediator in acetic-induced colitis in the rat. Agents Actions. 1991 Sep;34(1-2):181-4.