125552-93-4

125552-93-4 structure

Name: mvt 101
Chemical Name: mvt 101
CAS Number: 125552-93-4
Molecular Formula: C₃₅H₆₇N₁₁O₈
Molecular Weight: 769.97500
Catalog: Signaling Pathways Metabolic Enzyme/Protease HIV Protease
Create Date: 2018-06-02 22:13:54
Modify Date: 2024-01-18 19:16:01
Mvt-101 is a hexapeptide-based inhibitor of HIV-1 protease. Mvt-101 is also reduced-peptide-bond inhibitor. Mvt-101 inhibits reproduction of the HIV virus by blocking protease action[1].

Name	mvt 101
Synonyms	N-acetyl-Thr-Ile-Nle-ψ-[CH2N]-Nle-Gln-Arg-NH2 Ac-Thr-Ile-Nle-<CH2NH>Nle-Gln-Arg-NH2 Ac-Thr-Ile-Nle-(CH2NH)Nle-Gln-Arg-NH2 (S)-2-((S)-2-{(S)-2-[(2S,3S)-2-((2S,3R)-2-Acetylamino-3-hydroxy-butyrylamino)-3-methyl-pentanoylamino]-hexylamino}-hexanoylamino)-pentanedioic acid 5-amide 1-[((S)-1-carbamoyl-4-guanidino-butyl)-amide]

Description	Mvt-101 is a hexapeptide-based inhibitor of HIV-1 protease. Mvt-101 is also reduced-peptide-bond inhibitor. Mvt-101 inhibits reproduction of the HIV virus by blocking protease action[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease
References	[1]. Torbeev VY, et al. Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc Natl Acad Sci USA. 2011 Dec 27;108(52):20982-7.