29706-59-0

29706-59-0 structure

Name: lucidin 3-O-beta-primveroside
Chemical Name: lucidin 3-O-β-primeroside
CAS Number: 29706-59-0
Molecular Formula: C₂₆H₂₈O₁₄
Molecular Weight: 564.49200
Catalog: Research Areas Cancer
Create Date: 2018-03-01 01:31:39
Modify Date: 2024-01-04 18:01:32
Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts[1][2].

Name	lucidin 3-O-β-primeroside
Synonyms	1-Hydroxy-2-hydroxymethyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((2S,3R,4S,5R)-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-anthraquinone lucidin 3-O-β-D-primeveroside lucidin 3-O-β-purimeweroside ophiohayatone-B 2-carbinol-1,3-dihydroxyanthraquinone 3-O-β-primeveroside lucidine 3-O-β-primeveroside 1-hydroxy-2-hydroxymethylanthraquinone-3-O-β-D-primeveroside

Description	Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vivo	Lucidin primeveroside (0.3% in the diet; 4 weeks or 13 weeks) induces Lucidin-specific DNA adduct formation and increases mutation frequencies in mice[1].
References	[1]. Yockey OP, et, al. Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ. Chem Res Toxicol. 2017 Nov 20;30(11):2023-2032. [2]. Ishii Y, et, al. Effects of inhibition of hepatic sulfotransferase activity on renal genotoxicity induced by lucidin-3-O-primeveroside. J Appl Toxicol. 2019 Apr;39(4):650-657.

Hazard Codes	Xi