480-00-2

480-00-2 structure

Name: eleutherol
Chemical Name: eleutherol
CAS Number: 480-00-2
Molecular Formula: C₁₄H₁₂O₄
Molecular Weight: 244.24300
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-02-16 17:03:03
Modify Date: 2024-01-09 11:52:37
Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2].

Name	eleutherol
Synonyms	(R)-4-Hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-one (3R)-4-hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-one (3R)-4-Hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-on

Description	Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
Target	MIC: antifungal[1]
References	[1]. Adriana Campos, et al. Antifungal Activity of Pyranonaphthoquinones Obtained from Cipura paludosa Bulbs. Nat Prod Commun. 2015 Sep;10(9):1589-92. [2]. Tomohiro Ieyama,et al.α-Glucosidase inhibitors from the bulb of Eleutherine americana. Food Chem.2011 Sep 15;128(2):308-11.