eleutherol

Modify Date: 2024-01-09 11:52:37

eleutherol Structure
eleutherol structure
Common Name eleutherol
CAS Number 480-00-2 Molecular Weight 244.24300
Density N/A Boiling Point N/A
Molecular Formula C14H12O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of eleutherol


Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2].

 Names

Name eleutherol
Synonym More Synonyms

 eleutherol Biological Activity

Description Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2].
Related Catalog
Target

MIC: antifungal[1]

References

[1]. Adriana Campos, et al. Antifungal Activity of Pyranonaphthoquinones Obtained from Cipura paludosa Bulbs. Nat Prod Commun. 2015 Sep;10(9):1589-92.

[2]. Tomohiro Ieyama,et al.α-Glucosidase inhibitors from the bulb of Eleutherine americana. Food Chem.2011 Sep 15;128(2):308-11.

 Chemical & Physical Properties

Molecular Formula C14H12O4
Molecular Weight 244.24300
Exact Mass 244.07400
PSA 55.76000
LogP 2.78540
Storage condition -20°C

 Synonyms

(R)-4-Hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-one
(3R)-4-hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-one
(3R)-4-Hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-on
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